Optimal treatment for your pet requires a combination of home and professional veterinary care. Follow-up can be critical, especially if your cat does not improve rapidly.

Administer all prescribed medications and dietary changes as directed. Alert your veterinarian if you are experiencing problems treating your pet.

Initially, blood tests are taken every few weeks to monitor the cat's progress. Eventually the tests are then taken every four to six months. In some cases, a second liver biopsy is recommended to assess response to therapy after some time has passed.

The prognosis for cats with cholangiohepatitis is quite variable and unpredictable. Individuals with suppurative cholangiohepatitis may have an excellent response to therapy, return to normal and have no recurrence of the disease. If the cat is severely ill and debilitated at the time of diagnosis, however, the long-term outlook can be poor with suppurative cholangiohepatitis. With nonsuppurative disease, chronic, long-term remission is possible, although some affected individuals succumb to the disease regardless of appropriate therapy. The prognosis is usually worse if biliary cirrhosis is diagnosed, as the presence of scar tissue can indicate the liver has a poor capacity for recovery.