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Injection-Site Sarcoma (Vaccine-Site Sarcoma)

By: Dr. Debra Primovic

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Other conditions both benign and malignant can occur and are often confused with injection-site sarcoma. Following is a partial list of such swellings:

  • Subcutaneous abscess – a localized collection of pus in a cavity formed by the disintegration of tissue that is common in cats that roam and fight with other cats.

  • Infectious granuloma – an inflammatory mass associated with unusual bacteria or fungal infectious agents

  • Sterile granuloma – cat an inflammatory mass associated with administration of certain medications under the skin.

  • Panniculitis – cat the inflammation of the subcutaneous tissue

  • Steatitis – cat inflammation of subcutaneous fat

  • Epidermal inclusion cyst – cat a cyst in the outermost layer of skin derived from a hair follicle that has accumulated debris or fluid

  • Pilomatrixoma – benign tumor of the hair follicle

  • Sebaceous gland adenoma – cat a benign tumor of the glands that empty into the hair follicle

  • Other benign tumors

  • Chondrosarcoma – cat a malignant tumor derived from cartilage cells

  • Malignant fibrous histiocytoma – malignant tumor derived from tissue cells called histiocytes.

  • Mast cell tumor – malignant tumor derived from inflammatory tissue cells called mast cells

  • Lymphosarcoma – malignant tumor derived from immune cells called lymphocytes

  • Osteosarcoma – malignant tumor derived from bone cells

  • Rhabdomyosarcoma – malignant tumor derived from muscle

  • Sebaceous gland adenocarcinoma – malignant tumor derived from glands that empty into hair follicles

  • Apocrine gland adenocarcinoma – malignant tumor derived from sweat glands

  • Other malignant tumors

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