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Cryptococcosis in Dogs

By: Dr. Rosanna Marsalla

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Treatment

Treatment for cryptococcosis may include

  • Surgery to de-bulk lesions in the nasal cavity. The prognosis for recovery is poor when infected dogs have widespread nervous system involvement.

  • Anti-fungal drugs such as amphotericin B, flucytosine, ketoconazole, itraconazole, and fluconazole.

    Home Care and Prevention

    Administer as directed any medications prescribed by your veterinarian and follow recommendations for dietary modification. Long term treatment up to 6 months or more may be required. Observe your pet's general condition: Watch for worsening of symptoms and bring any changes to the attention of your veterinarian.

    Some anti-fungal medications (e.g. ketoconazole, itraconazole) have the potential to cause liver damage. The animal should have periodic blood tests performed to evaluate for the presence of liver damage. These medications should be administered with food and they may cause vomiting or diarrhea.
    Amphotericin B has the potential to cause kidney damage and must be given by intravenous infusion after being diluted in a 5 percent dextrose solution. The animal should have periodic blood tests performed to evaluate for the presence of kidney damage.

    The possible sources of infection for affected animals should be evaluated because these areas represent potential sources of exposure and infection for human beings as well, especially children, immunosuppressed patients, and the elderly.

    Restrict animals from areas that contain large amounts of pigeon droppings, especially shady, damp buildings. Areas where pigeons reside should be cleaned with hydrated lime diluted in water and sodium hydroxide solution.

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