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Dog and Cat Fleas: Pour-on Products to Kill Fleas

By: Dr. Debra Primovic

Read By: Pet Lovers
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Product NameActionRx or OTCFrecuency of AdministrationNotes
Imidacloprid (Advantage®)
Prevents and kills fleas.
Available both as Rx and OTC. Recommended monthly application. Water-resistant. For dogs over 7 weeks and cats over 8 weeks of age.
Fipronil
(Frontline Top Spot®)
Kills adult fleas and ticks.
Available both as Rx and OTC. Recommended application monthly for flea and tick control. May use every 1 to 3 months for flea control only. Waterproof. For dogs and cats over 8 weeks.
Fipronil combined with methoprene
(Frontline-Plus®)
Prevents all flea stages from developing and kills fleas and ticks.
Available both as Rx and OTC. Recommended application monthly for flea and tick control. May use every 1 to 3 months for flea control only. Waterproof. For dogs and cats over 8 weeks.
Selamectin (Revolution®)
Prevents heartworm disease, kills fleas and controls ear mites. Treats sarcoptic mange and tick infestations in dogs. Treats and controls hookworms and roundworms in cats.
Available as Rx only. Recommended monthly application. Waterproof. For dogs 6 weeks of age or older. For cats 8 weeks of age or older.
Product NameActionRx or OTCFrecuency of AdministrationNotes
Permethrin
combined with imidacloprid
K9Advantix®
Prevents and kills fleas, ticks and mosquitoes.
Available both as Rx and OTC. Recommended monthly application. Waterproof. Water-resistant. For dogs 7 weeks and older.

Permethrin should not be used in animals with known hypersensitivity or allergy to the drug. This drug should be avoided in geriatric or very ill or weak animals.

Permethrins should never be used in cats. Homes with cats that are known to groom dogs should not use this product.
Permethrin
combined with pyriproxyfen
Bio Spot for Dogs®
Prevents and kills fleas, ticks and mosquitoes.
Available as OTC. Recommended monthly application. Re-application may be necessary after shampooing.

For dogs 12 weeks and older.
Permethrin should not be used in animals with known hypersensitivity or allergy to the drug. This drug should be avoided in geriatric or very ill or weak animals. Homes with cats that are known to groom dogs should not use this product. Permethrins should never be used in cats.

May not be available in some states.
Ethofenprox combined with pyriproxyfen
Bio Spot® for Cats and Ferrets
Spot-on product prevents development of juvenile fleas and flea eggs for up to 3 months.

Additional use of Flea Halt!® (pyrethrin) towelettes eliminate adult fleas, deer ticks, and mosquitoes for up to 3 weeks.

Available as OTC. Re-application every 3 months with spot-on product. Use of towlette product every 3 weeks.
endcell}
Re-application may be necessary after shampooing.

For cats 12 weeks and older and ferrets 16 weeks and older.

For products containing pyrethrins, use with caution in cats.
Etofenprox and methoprene
Zodiac® Spot-on Plus for Cats
Kills and repels fleas, ticks and mosquitoes.
Available as OTC. Recommended monthly application. May not be available in some states. endcell}

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