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SENTINEL® (milbemycin oxime - lufenuron)

By: Novartis Animal Health

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Parasitic infections are extremely common in dogs and can lead to major symptoms of disease. Fortunately, many of the most common and important parasites – heartworm, fleas and intestinal worms (roundworms, hookworms and whipworms) – can be prevented or controlled. SENTINEL (milbemycin oxime - lufenuron) Flavor Tabs protect against five parasites at once. SENTINEL Flavor Tabs guard against heartworms and fleas, as well as roundworms, hookworms (A. caninum) and whipworms. SENTINEL Flavor Tabs are clean, safe, and effective.


SENTINEL Flavor Tabs have been tested to satisfy FDA requirements (NADA #141-084, Approved by the FDA). They have been used by millions of dogs around the globe and are even safe for puppies four weeks and older, weighing over two pounds.

As with other heartworm preventives, dogs must be tested for heartworm prior to using SENTINEL Flavor Tabs. In a small percentage of dogs treated with SENTINEL Flavor Tabs, digestive, neurological and skin side effects may occur.


SENTINEL Flavor Tabs have been proven effective against five major parasites. They are 100% effective in preventing heartworm. In a three year study, the ingredient in SENTINEL Flavor Tabs that protects against fleas demonstrated 100% effectiveness in preventing flea populations.*

(*"Efficacy of Orally Administered Lufenuron to Control and Prevent Flea Infestations" conducted by Michael Dryden, DVM, PhD, and Alberto Broce, PhD, Kansas State University, Manhattan, KS.)

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