Clindamycin for Dogs and Cats
Overview of Clindamycin for Cats and Dogs
Clindamycin, commonly known by the brand names Antirobe® and Cleocin®, is an antibiotic frequently prescribed for dogs and cats to treat certain bacterial infections. It works by inhibiting bacterial protein synthesis, which prevents bacteria from growing and multiplying. This mechanism of action is similar to that of erythromycin and related antibiotics. Clindamycin is also chemically related to lincomycin (Lincocin®).
This medication is effective against a relatively narrow range of bacteria but is particularly useful for infections affecting the skin, oral cavity, bones, and respiratory tract in dogs and cats. Because of its targeted spectrum, clindamycin is most effective when used for specific, diagnosed bacterial infections. It is a prescription medication and can only be obtained through a veterinarian or with a valid veterinary prescription.
Brand Names and Other Names of Clindamycin
Clindamycin is approved for use in both human and veterinary medicine. In human medicine, it is commonly marketed under the brand name Cleocin® by Upjohn. The veterinary formulation is sold as Antirobe®, also produced by Upjohn. Despite differences in labeling, the active ingredient is the same.
Uses of Clindamycin for Dogs and Cats
Clindamycin is widely used in dogs and cats to treat a variety of bacterial infections, including skin infections, wound infections, bone infections, pneumonia, and dental or other infections of the oral cavity. It is especially effective against anaerobic bacteria, which are bacteria that grow in low-oxygen environments and are commonly found in deep wounds and dental infections.
In some cases, clindamycin has been used to treat protozoal infections in animals, although its effectiveness for this purpose has been debated and is not universally accepted. It is important to note that clindamycin is not effective against infections caused by parasites such as intestinal worms, mites, viruses, or fungi.
Precautions and Side Effects
Clindamycin is generally considered safe and effective when prescribed and monitored by a veterinarian, but side effects can occur in some animals. It should not be used in pets with a known allergy or hypersensitivity to clindamycin or related antibiotics. Because clindamycin can interact with other medications, particularly certain antibiotics, pet owners should inform their veterinarian about all medications and supplements their pet is currently receiving.
The most common side effects associated with clindamycin in dogs and cats include vomiting, diarrhea, and a decreased appetite. Cats, in particular, may strongly dislike the taste of the liquid formulation, which can lead to medication refusal or excessive drooling after administration.
How Clindamycin Is Supplied
Clindamycin is available in several oral formulations to accommodate different dosing needs. These include capsules in 25 mg, 75 mg, and 150 mg strengths, as well as an oral liquid suspension containing 25 mg of clindamycin per milliliter.
Clindamycin Dosage for Dogs and Cats
Clindamycin should never be given to pets without first consulting a veterinarian. If you’re concerned about costs related to medication, pet insurance may be able to help. Click here to learn more.
The appropriate dose depends on the species, body weight, and type of infection being treated. In dogs, the typical dose is 5 mg per pound (11 mg/kg) given orally every 12 hours, or 10 mg per pound (22 mg/kg) given once every 24 hours.
For cats, dosing generally ranges from 2.5 mg per pound (5.5 mg/kg) every 12 hours to 10 mg per pound (22 mg/kg) every 24 hours, depending on the nature and severity of the infection. In both dogs and cats, clindamycin tablets or capsules should be followed by a small amount of water or food to help ensure the medication reaches the stomach. This is especially important in cats, as dry pills can become lodged in the esophagus and cause injury.
The length of treatment varies based on the condition being treated, how well the pet responds to therapy, and whether any side effects develop. It is important to complete the full course of medication exactly as prescribed, even if the pet appears to be feeling better. Stopping treatment too early can lead to relapse or contribute to antibiotic resistance unless otherwise directed by a veterinarian.