Permethrin (Kiltix®, ProTICall®, K9 Advantix®)
By: Dr. Dawn Ruben

Overview

Insecticides have been around for many years. One of the more popular insecticides belongs to a group known as pyrethrins. These medications are placed on the animal's skin to kill fleas and ticks.

Pyrethrins were originally developed from the Chrysanthemum plant and work by affecting the nervous system of the insect, resulting in death.

As science progressed, synthetic forms of pyrethrins were developed, including permethrin. This product has more stability and potency than the natural pyrethrins.

Permethrins are able to repel various species of ticks before they have a chance to attach.

This drug has residual action and is only applied once a month.

Permethrin is available without a prescription but should not be administered unless under the supervision and guidance of a veterinarian.

Brand Names or Other Names

This drug is registered for use in animals only.

Human formulations: None

Veterinary formulations: Kiltix® (Bayer), ProTICall® (Schering-Plough), K9 Advantix® (Bayer) and various over-the-counter formulations

Uses of Permethrin

Permethrins are used to kill fleas and ticks in dogs.

Precautions and Side Effects

While generally safe and effective when prescribed by a veterinarian, permethrin can cause side effects in some animals.

Permethrin should not be used in animals with known hypersensitivity or allergy to the drug.

Permethrins should never be used in cats.

This drug should be avoided in geriatric or very ill or weak animals.

Homes with cats that are known to groom dogs should not use this product.

Permethrins are recommended in dogs over 7 weeks of age.

Adverse effects of the drug are minimal if used properly. Redness of the skin in the area of the drug application may occur.

Dogs that lick the product may drool or vomit.

How Permethrin is Supplied

Permethrin is available in 45 percent concentration and 65 percent concentration. The drug is a liquid packaged in precisely measured 1.5 ml tubes.

K9 Advantix® is available as permethrin combined with imidacloprid.

Dosing Information

Medication should never be administered without first consulting your veterinarian.

For dogs under 33 pounds, one applicator tube is used. The drug is applied on the skin between the shoulder blades.

For dogs 33 to 65 pounds, two applicators are used.

For dogs over 65 pounds, four applicators are used.

The duration of administration depends on the condition being treated, response to the medication and the development of any adverse effects.

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