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TrizEDTA (Dermapet)

By: Dr. Dawn Ruben

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  • Ear infections are common problems, often caused by bacterial, fungal or parasitic infections, and treated with various medications. Pseudomonas is one of the bacteria often found associated with ear infections.
  • TrizEDTA is a buffer solution used primarily to treat ear infections, especially those contaminated with the bacteria Pseudomonas. When used in conjunction with other medications, it has been shown to also be effective in treating ear infections caused by other bacteria but is not effective in treating yeast or parasite infections.
  • TrizEDTA works by affecting the integrity of the bacterial cell wall, resulting in death of the bacteria. It also reduces the acidity within the ear canal slowing the growth of bacteria and helps breakdown inflammatory debris, making it easier to remove for the ear canal.
  • The effects of TrizEDTA are enhanced when used in conjuction with certain antibiotics.
  • Once the ear infection has resolved TrizEDTA can also be used as part of a routine ear cleaning regimen to prevent recurrence.
  • TrizEDTA is available over the counter but should not be administered except under the supervision and guidance of a veterinarian.

    Brand Names and Other Names

  • This drug is registered for use in animals only.
  • Human formulation: none
  • Veterinary formulations: TrizEDTA (DermaPet)

    Uses of TrizEDTA

  • TrizEDTA is used in the treatment of bacterial ear infections.
  • TrizEDTA can be used as part of a cleaning regime to prevent ear infections.

    Precautions and Side Effects

  • While generally safe and effective when prescribed by a veterinarian, TrizEDTA may cause reactions in some animals.
  • TrizEDTA should not be used in animals with known hypersensitivity or allergy to the drug.
  • TrizEDTA should be discontinued if it is associated with excessive irritation, or if the condition continues to worsen despite several days of treatment. It is important to contact your veterinarian in either case.
  • TrizEDTA is designed for topical use only; it should not be taken internally.
  • The drug should not come into contact with the eyes.

    How TrizEDTA is Supplied

  • TrizEDTA is available in a 4 ounce and 16 ounce aqueous flush
  • It is also available in 4 ounce and 16 ounce crystals.

    Dosing Information

  • TrizEDTA should be applied to the ear 30 minutes before other medications are placed in the ear.
  • As part of a cleaning regime, TrizEDTA is applied to each ear canal two to three times per week.
  • The duration of administration depends on the condition being treated, response to the medication and the development of any adverse effects. Be certain to complete the prescription unless otherwise directed by your veterinarian. Even if your pet feels better, the entire treatment plan should be completed to prevent relapse.

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