Urolithiasis-Urate in Cats

Urate Urinary Tract Stones in Cats

Urate uroliths, also referred to as calculi, are stones within the urinary tract composed of ammonium urate. Urate urolithiasis is uncommon in cats.

The average age of onset for cats with portosystemic shunts is less than one year, whereas the average age of onset for cats without portosystemic shunts is greater than three years of age. Clinical symptoms depend on the size and number of uroliths as well as their location within the urinary tract. Some affected animals may have no clinical symptoms.

Causes of Urate Urinary Tract Stones in Cats

What to Watch For

Occasionally, nervous system abnormalities (dull mental attitude, head-pressing, seizures) may be observed in animals with portosystemic shunts.

Inability to urinate may be seen in animals with urethral obstruction. Urethral obstruction constitutes a medical emergency and you should take your pet to your veterinarian immediately.

Diagnosis of Urate Urinary Tract Stones in Cats

Routine tests include a complete blood count (CBC), biochemical profile and urinalysis. Changes such as low blood urea nitrogen (BUN), low blood sugar, and low protein concentrations may be seen in animals with portosystemic shunts. Kidney impairment (high BUN and serum creatinine concentrations) may be seen in animals with urinary tract obstruction or related kidney disease. Urate crystals are present in the urine in some but not all cases.

Additional tests include:

Treatment of Urate Urinary Tract Stones in Cats

It is important to establish whether or not the affected animal is in need of emergency care or hospitalization. Examples of emergency situations include animals with urethral obstruction, severe kidney failure, and those with hepatic encephalopathy, which are nervous system signs secondary to a portosystemic shunt.

Surgical intervention depends upon the location and size of the calculi, in addition to the clinical symptoms present in the patient. In addition, surgical repair may be warranted in pets with portosystemic shunts.

Additional treatment includes:

Home Care and Prevention

Administer as directed all medications prescribed by your veterinarian. Also, follow dietary and feeding recommendations and follow up with your veterinarian as directed. Recurrence of urate urolithiasis is common.

Consider special diets in those breeds with a predilection to urate calculi, specifically low protein alkalinizing diets that increase urine pH. If your pet is diagnosed with a portosystemic shunt, appropriate medical or surgical therapy should be instituted at once so as to reduce the risk of forming urate calculi.