15 MORE Human Over-the-Counter Drugs Safe for Dogs

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The dosage for Zeel® tablets in dogs is one tablet every 8 hours for 2 weeks then decrease to every 12 hours for maintenance. Learn more about how to safely dose Zeel in dogs. 

22. Acetylsalicylic acid (Aspirin)

Acetylsalicylic acid (ASA), or more commonly known as aspirin, belongs to the group of non-steroidal anti-inflammatory drugs commonly abbreviated as NSAIDs. It is commonly used in dogs to treat minor pain and inflammation for chronic conditions like arthritis.  It can also reduce fevers and can reduce a chemical that is important in the effectiveness of platelets. This results in platelets losing their ability to clump together to prevent bleeding.

Aspirin can upset the stomach and intestines due to its irritating chemical nature and because it blocks the beneficial body chemicals that protect the linings of those organs. Therefore, stomach irritation cannot always be prevented by giving the drug with food or by using a “buffered” or coated aspirin tablet.

Aspirin may interact with other medications and should never be used with other non-steroidal anti-inflammatory drugs (such as Rimadyl, Novox, Meloxicam, Deramaxx and many more) and steroids (such as Prednisone).

To be safest, never administer aspirin to your dog without consulting your veterinarian because there are many drug interactions and side effects.

In healthy dogs that are taking no other medications, a typical dose is 5 to 10 mg per pound (10 to 20 mg/kg) twice daily for dogs. Read more about the safety of and dosing Aspirin in dogs. Please see and talk to your veterinarian before giving more than a dose or two. There are better alternatives available as a prescription product.

23. Ibuprofen (Advil® or Motrin®)

Ibuprofen, commonly known by the brand names of Motrin® or Advil® and may more can be used in dogs to reduce swelling and inflammation, most commonly from arthritis and musculoskeletal pain.  Ibuprofen belongs to a general class of drugs known as non-steroidal anti-inflammatory drugs (NSAID). While NSAID’s are effective in reducing pain, inflammation, and fever, they carry the risk of causing stomach ulcers, liver injury, and kidney damage in animals. Ibuprofen needs to be given with special care.

Ibuprofen is commonly used on a short-term basis in dogs and can NEVER be given to cats.  Ibuprofen should ONLY be used under the guidance of a veterinarian. It should NEVER be given with other NSAID drugs such as aspirin, Novox, Meloxicam, Rimadyl, Deramaxx and many more or steroids such as prednisone or dexamethasone. Used improperly, ibuprofen can be highly toxic.  Learn more about how to safely dose Learn more about how to safely give Ibuprofen to dogs.

24.  Naproxen (Aleve®)

Naproxen, commonly known as Aleve or Naprosyn, is used to alleviate pain and inflammation in dogs. Naproxen belongs to a general class of drugs known as non-steroidal anti-inflammatory drugs (NSAID) that work to reduce pain, inflammation, and fever. There is no safe dose for cats!  If given to dogs, the dose ranges from 0.5 to 1.5 mg per pound once daily. Most veterinarians prefer and recommend other non-steroidal anti-inflammatory drugs (NSAID) over Naproxen that has proven to be safe and effective for dogs. If you believe your dog needs a non-steroidal anti-inflammatory drug, please talk to your veterinarian for recommendations. Learn more about how to safely dose Naproxen.

Medications for Cough

25. Dextromethoraphan (Robitussin DM®) 

Dextromethorphan, commonly known by the brand name Robitussin-DM®, can be used in dogs to suppress and alleviate coughing. It is considered a mild cough suppressant. It can be prescribed in dogs with conditions such as tracheobronchitis (kennel cough), chronic bronchitis, tracheal (windpipe) collapse and bronchial compression.

In dogs, the dose given is 0.5 to 1 mg per pound (1 to 2 mg/kg) every 6 to 8 hours. Does as high as 5 mg per pounds may be used twice daily in some situations.  Many veterinarians recommend doses of anywhere from 1 ml to 2 ml per 10 pounds of body weight.

Please note that some veterinarians do not recommend cough suppressant with some conditions. A cough is Mother Nature’s way of clearing something from the airway which can be an important mechanism. By suppressing the cough, you may be allowing secretions to fall deeper into the respiratory tract. Please see your veterinarian if your dog is coughing to help you determine the underlying cause of the cough and help you establish if Robitussin DM® is safe for your dog.

Learn more about how to safely use dextromethorphan in dogs.

26. Pseudoephedrine  (Sudafed®)

Pseudoephedrine HCL, commonly known by the brand names Sudafed® or Equiphed®, is a drug that can be used to treat respiratory conditions such as bronchitis and nasal congestion. It can also increase urethral tone in dogs with abnormalities.


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