Cervical Vertebral Instability (Wobbler Syndrome) in Dogs Page 2


Disk Herniation

The second disease syndrome is seen in adult dogs arising from type II disk herniation with accompanying vertebral ligamentous hypertrophy caused by vertebral instability. This disease affects the disk spaces C5-6 and C6-7 but C3-4 and C4-5 may be affected. Multiple disk spaces may be affected. This disease entity is seen in mature dogs between three- and eleven-years-old with an average age of six years.

In the disease seen in the older Doberman pinschers, it is usually caused by a disk degeneration secondary to vertebral instability.

Other breeds that can be affected with Wobblers Disease include:

  • Mastiff
  • Rhodesian ridgeback
  • Irish wolfhound
  • Irish setter
  • Rottweiler
  • Labrador retriever
  • German shepherd
  • Golden retriever
  • Weimaraner
  • Great Pyrenees
  • Bernese Mountain Dog
  • Bouvier des Flandres
  • St. Bernard
  • Swiss Mountain Dog
  • Mixed breed dogs

    Dogs that have been diagnosed with Wobblers Syndrome should not be used for breeding or work.

    Other diseases that mimic Wobbler Syndrome include:

  • Trauma – car accidents or wounds from bullets or arrows
  • Diskospondylitis – in infection of the disk space and vertebrae
  • Cancer – primary or secondary (metastatic disease)
  • Inflammation or infection of the spinal cord
  • Juvenile orthopedic diseases – hypertrophic osteodystrophy, panosteitis, osteochondrosis dessicans

    In-depth Information on Diagnosis

    Your veterinarian will perform a complete physical and neurological examination to assess the location and severity of the problem. Additional tests may include:

  • Baseline laboratory work consisting of a CBC, chemistry profile and urinalysis
  • Doberman pinschers and some of the older dogs should be tested for hypothyroidism. Hypothyroidism is not a cause of the disease but may impact treatment outcomes.
  • If surgery is contemplated, Doberman pinschers and other susceptible dogs should be tested for the bleeding disorder caused by Von Willebrand’s disease.
  • Survey cervical radiographs. These radiographs are essential to make sure that some of the other diseases are not present including diskospondylitis, large bony tumors, fractures or other trauma.

    Radiographs will show a number of abnormalities associated with Wobblers disease including:

  • Tipping of the vertebrae into the spinal cord
  • Stenosis (narrowing) of the vertebral canal
  • Malformation of the vertebral bodies
  • Narrowing of the intervertebral disk space with arthritic changes

    Depending on your veterinarian’s expertise and access to special imaging techniques, your pet may be referred to a specialist such as a neurologist-neurosurgeon for additional tests, such as:

  • Neuro-imaging by myelogram, CT-myelogram, or magnetic resonance imaging is required for diagnosing Wobblers disease in the dog. Neuroimaging allows determination of the exact location of the compression, the degree of compression and some prognostic information.
  • The choice of imaging techniques usually depends on your veterinarian’s access and familiarity with some of the imaging modalities.
  • A CSF tap may be performed to assess for inflammatory-infectious diseases before performing a myelogram.

    Anesthesia is required for CSF tap and neuro-imaging. Anesthesia may make some dogs worse following the neuroimaging procedure. Most dogs that undergo myelograms and CT-myelograms become worse. This worsening is typically transient but can be permanent. Discuss the benefits and risks of the CSF tap and imaging with your veterinarian.

  • In-depth Information on Treatment

    Medical Treatment for Wobblers Syndrome

    Dogs that are mildly or intermittently affected may be treated conservatively with restricted activity, nonsteroidal anti-inflammatory drugs, feeding from a height and the use of a chest harness rather than a collar.

    Dietary adjustment, if necessary, in young dogs as this appears to be associated with the disease seen in young, growing, giant breed dogs such as Great Danes. Dietary adjustment must be made slowly and with caution. Your veterinarian may recommend a nutritional consult to give your dog a strong chance for recovering from this disease.

    Medical treatment consisting of glucocorticosteroids may alleviate some signs of disease but effects may be temporary and may cause gastroenteritis and cystitis.

    A neck brace or cast may be recommended. Medical therapy may make your dog’s condition degenerate. If you notice your dog’s clinical signs worsening, notify your veterinarian immediately. It usually indicates failure of medical therapy. Your dog may require surgical intervention.

    Acupuncture or other alternative therapies may help your dog. Be cautious in allowing chiropractic adjustments to a moderately or severely affected dog.

    Surgical Treatment for Wobblers Syndrome

    Moderately or severely affected patients usually require surgery to treat the spinal cord compression. There are veterinary neurosurgical specialists that do these kinds of procedures. Make sure you understand the risks of surgical treatment.

    In long standing compression, neurological deficits may be permanent. Surgical goal in these patients is to arrest the disease process. Understand from your veterinarian the goal in your pet before surgical intervention is performed. In general, the best surgical candidates are those that are still strongly ambulatory. Patients that cannot stand or walk have a very guarded prognosis. If your dog is quadraplegic or paralized, a long recovery is likely and some dogs will never be able to walk no matter how talented your neurosurgeon is or how dedicated you are.

    Surgical treatment is aimed at decompression (relieving the impingement of the spinal cord) and depending on the nature of the lesion, fusion or stabilization may be needed. Stabilization may require the insertion of bone cement or screws into the vertebrae. Some dogs may benefit from having a neck brace or cast placed post-operatively.


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