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Diabetes in Dogs – A Guide to Understanding and Treating Your Dog

Diabetes mellitus, commonly known by the shortened name “diabetes”, sugar diabetes or “sugar”, is one of the most frequent and important medical disorders of both humans and dogs. As a pet owner with a newly diagnosed dog with diabetes, it is difficult to know what you need to do. We created this article to help you know step by step what you need to know and what you need to do and to answer common questions that come up with new diabetic dog owners.

The 6 keys to treatment of diabetes in dogs include:

  1. Change your dog’s diet
  2. If your dog is overweight – help your dog lose weight
  3. Give insulin every 12 hours
  4. Monitor for response to treatment
  5. Maintain a consistent diet, exercise and insulin treatment plan
  6. Monitor for complications of the disease

We will help you understand more about diabetes, how and when to give insulin how to deal with complications. We also included answers to the most common questions diabetic dog owners have as they start their journey as a diabetic dog owner.

What is Diabetes?

Diabetes is a disease that leads to chronic elevation of the blood glucose or sugar. Blood sugar is maintained by a group of hormones, the most important of which is insulin, which is manufactured by the pancreas, a small organ near the intestines. Insulin lowers the blood sugar after a meal, and deficiency of insulin, or an insensitivity of body cells to available insulin, leads to diabetes.

With good care, your dog can have a very good life with diabetes. We will help tell you how.

What Dogs Get Diabetes?

Diabetes mellitus usually affects middle-aged to older dogs of either sex, however it is most common in female dogs (twice as common in females as in males). The peak age seen in dogs is 7 to 9 years. Juvenile-onset diabetes may occur in dogs less than 1 year of age. Any breed can be affected but some breeds are at higher risk.

Breeds at increased risk for diabetes mellitus include the Australian terrier, Samoyed, Schnauzer (miniature and standard), Bichon frise, Cairn terrier, Keeshond, Spitz, Fox terrier and the Poodle (both miniature and standard).

What Causes Canine Diabetes?

The cause of diabetes has a lot to do with genetics and bad luck. There are risk factors which can potentiate diabetes such as obesity, recurring pancreatitis, Cushing’s disease (hyperadrenocorticism), and drugs such as glucocorticoids and progestogens that antagonize insulin.

What are Common Symptoms of Diabetes?

Common symptoms of diabetes in dogs include thirst and increased water consumption among others. For more detailed information about the diagnosis, treatment and complications of diabetes, go to: Diabetes in Dogs.

Uncontrolled elevation of glucose leads to dehydration and body chemistry disorders that can eventually cause coma and death. Left uncontrolled, diabetes can become life threatening.

Why Does My Diabetic Urinate More?

When a pet is diabetic, the body tries hard to fix the problem. For example, the kidneys will try to get rid of excess glucose in the urine. To get rid of extra glucose they also end up getting rid of a lot of extra water. So they urinate more. Because they urinate more and are getting rid of a lot of extra water, they are thirsty and drink more.

Classic signs of diabetes is drinking more and urinating more. The medical term for this is polydipsia (drinking more) and polyuria (urinating more).

What Does the Term Spilling Glucose Mean?

Some clients hear their vet say this term – their dog is “spilling glucose”. This term means that their dog has glucose in the urine. This is the body’s way of trying to get rid of excess glucose in the dog’s blood.

How is the Diagnosis Obtained?

The first step in treating diabetes in your dog is getting a correct diagnosis. This requires a veterinary examination and appropriate tests, such as a urinalysis (to detect spilled “sugar”) and blood glucose determination. Additional tests often are needed to assess the overall medical situation. Once the diagnosis is made, however, you and your veterinarian can work together to effectively control diabetes mellitus.

What Type of Diabetes Does My Dog Have?

There are two basic forms of diabetes: type I and type II. Absolute deficiency of insulin leads to type I diabetes. This is due to an insufficient number of insulin-producing pancreas cells. Type I diabetes, often called “juvenile-onset diabetes” in people, and represents the most serious form of the disease. Effective treatment for type I diabetes requires a combination of controlled diet, regular exercise and insulin therapy.

Dogs are most often affected by type I diabetes and rarely have type II. People and pets with type I diabetes require daily injections of insulin to maintain a regular blood-sugar level.

Adult onset or type II diabetes is the more common form of diabetes in people. This condition combines a relative lack of insulin production with a resistance of body cells to the effects of the hormone. Type II diabetes is treated with a combination of diet, weight control and medicine that makes cells more sensitive to insulin. This form of diabetes is observed more often in cats than in dogs. Keys to successful treatment are a high-fiber diet, weight control and occasionally, medicines designed for humans to control the glucose level.

How Do I Treat Diabetes?

The treatment of diabetes requires the administration of injectable insulin to drive sugar molecules into the body’s needy cells. Dietary changes will help.

You will need to learn how to give your dog insulin as well as how, what and when to feed your dog.

For dogs that are extremely ill, they will require hospitalization until the diabetes can get is under control.

What Should I Expect From My Vet?

Every veterinary clinic and vet is a little different in how they schedule rechecks following the diagnosis of diabetes.

One approach is as follows (and may vary with your individual veterinarian):

  1. The first appointment should include information about diabetes, demonstrate how to give insulin, and dietary recommendations.
  2. A recheck should be scheduled in one week that includes a clinical examination, history of the symptoms, a serum fructosamine level and a 12-hour blood glucose curve to be performed at the hospital. Treatment should be adjusted if necessary. Some vets will discuss the advantages of home monitoring and see if they you are interested in doing this at home. If you are interested in doing home monitoring, you’ll need to order the monitor and strips before your next appointment.
  3. Two weeks later another recheck is performed. (Providing everything is okay), which is 3 weeks from the original diagnosis. At this appointment you may learn how to perform home monitoring techniques with your glucometer. You vet’s office should show you how to use this machine and allow you to demonstrate how to obtain a blood glucose on your dog. You should also learn to calibrate your machine.
  4. Additional rechecks should be scheduled as needed which ends up being monthly for 3 months, then every 2 months for 2 visits then every 6 months if things are going well.
  5. When you are comfortable with using the glucometer at home, testing the blood glucose before your dog eats is recommended twice weekly for at least a month to help determine signs of a low blood sugar. If the blood sugar is less than 100 mg/dl – call your veterinarian to determine if they want to lower the insulin dose.
  6. If you will be doing home glucose curves, they should be done prior to your monthly appointment. Results should be emailed, faxed or dropped off prior to the appointment if possible. This will give your vet time to reevaluate and recommend any adjustments. Coordinate what schedule works best with your veterinarian.

Will My Diabetic Dog Need to be Hospitalized?

If your pet has stopped eating, has been vomiting, and is generally not doing well; chances are we will admit your dog into the hospital to begin treatment. This often happens when the diabetes mellitus has progressed and the body will produce ketones.

Because the body has not been able to use glucose as its energy source, instead it will begin to use its fat. When the body burns fat for energy, a by-product known as ketones are created and unfortunately they are toxic. Ketones can be found in urine samples.

Once ketones are present the animal will continue to decline rapidly unless treatment begins. The presence of Ketones changes the diagnosis to Diabetic Ketoacidosis which can be complicated to treat.

Diabetic ketoacidosis (DKA), the most severe form of Diabetes Mellitus, results in severe changes in blood chemicals including imbalances in small, simple chemicals known as electrolytes.

In-hospital therapy generally includes insulin administration with frequent dose adjustment (every few hours), intravenous (IV) fluids, administration of electrolytes (blood chemicals), treatment of secondary problems, and antibiotics. Multiple blood glucose samples are taken to determine the insulin dose and urine samples to determine the presence of ketones. The insulin given in this situation is a short acting insulin and will not be the insulin used when you go home.

The process is slightly different with every dog but will generally require two to four days of intense hospitalization.

What are Signs of Diabetic Keotacidosis (DKA)?

Symptoms include weight loss, lack of appetite, increased thirst, frequent urination, lethargy, disorientation, vomiting, and some people notice a fruity smell to the breath (acetone odor).

If you suspect your dog is having symptoms of DKA, this is a life-threatening emergency. Call your veterinarian immediately. Treatment includes hospitalization, intravenous fluids, and frequent doses of short-acting insulin. For more information, go to: Diabetic Ketoacidosis (DKA) in Dogs.

Beginning Treatment With Your Diabetic Dog

If your pet is still feeling good, eating with no vomiting, you will be taught to give insulin injections to your dog and start them on a special diet. Below is information on what and when to feed your diabetic dog.

The goal of diabetes treatment is to control the blood glucose so it is close to the normal range, as it would be if the pancreas were still producing insulin naturally.

What Diet Should I Feed My Diabetic Dog?

Your dog’s weight and what your dog eats has a direct impact on his blood glucose levels. A lot of research exists and is underway regarding the best diet to feed diabetic dogs.

Current research suggests that a diet high in fiber, low in simple sugars, and moderately restricted in fat and protein to attain an ideal weight is best. Fiber in the diet helps your dog feel full, but also helps slow the entrance of glucose into your dog’s bloodstream. This can be in either a canned or dry formula or a combination of both.

Your veterinarian should determine how many calories your dog needs every day, based on his weight, body condition and activity level. Once you know that number, divide the total calories per day into his meals and treats. It’s important stay within those calories and be consistent.

Overweight dogs are generally placed on a diet designed for weight loss. Keeping your dog at an ideal weight is critical. Losing the extra weight can help your dog better use the insulin and make it easier for him to turn the food in to fuel. In addition, dogs with diabetes that are well maintained have less problems with diabetes related complications such as cataracts, pancreatitis, and urinary tract infections.

Normal weight dogs are generally placed on a good quality food to maintain body weight.

What diet works well for one dog may not work well for another. Every dog is a little different. You may need to change the timing of meals and injections to find what works best your dog.

Diets recommended by some vets include:

IMPORTANT: The most important aspect to a diabetic diet is that it is complete, balanced, your dog likes it, you are feeding the calories your dog needs and you are consistent. Feed the same food and the same amount of calories every day. This will help keep glucose levels steady.

Encourage your dog to drink plenty of fresh clean water.

How Do I Calculate How Many Calories My Dog Should Eat Per Day?

Your vet can help you with this. Here is a method for calculating your dog’s calorie requirements. Go to How to Calculate Your Dog’s Daily Calorie Intake

Can I Treat My Dog with Diabetic Pills?

Many adult humans have adult onset type II diabetes which can be controlled with oral medications. These medications don’t work in dogs. Dogs have insulin dependent Type I Diabetes Mellitus.

My Dogs Hates His New Food, What Should I Do?

If your dog won’t eat his new food, go back to his regular food for a while. It is important that your dog eat. Then do a gradual change. Mix in maybe 10% the new food with 90% of the prior food. Each day, add a few more kibbles of the new food to the old food until have obtained a 100% change to the new food. If he still will not eat the new diet, refer to the list of recommended foods above and discuss a different option with your veterinarian.

When Should My Dog Eat?

For dogs that are getting insulin twice daily, it is recommended to split the daily calories in to two meals, which are fed before the insulin dose.

For dogs on once daily insulin, they should be fed also twice daily with the first meal before the insulin injection and the second meal at the time when the insulin peaks which can be determined based on knowledge of the insulin and the glucose curve.

Most diabetic dogs are fed twice daily. Give ½ of the daily calories approximately 30 minutes before the insulin injection. After your dog eats, his blood glucose will naturally increase. The insulin will help drive the glucose levels back to a normal level. Give the other half of the daily calories before the second insulin injection (this is assuming you are giving insulin every 12 hours).

Another method is to feed your diabetic dog ¼ of its daily calories in the morning before the insulin injection, and another ¼ of the calories 6 hours later when the insulin is peaking, another 1/4 of the calories at dinner and the last fourth 6 hours later.

Can I “Free Feed” My Dog?

Free feeding is a term that refers to having food in the bowl all the time and allowing your dog to eat when he wants.

Many dogs with diabetes are on a strict consistent feeding schedule. However, this can be difficult for some dogs. This may work better for dogs that are nibblers and not food motivated.

Scheduled feedings work best on dogs that are food motivated and gobble their food or dogs in multi-pet homes.

Can My Dog Get Treats?

Diabetic dogs can get treats as long as they are approved by your vet. Generally treats that are low in sugar and carbohydrates are ok. Larger treats can even be broken up into small pieces to provide multiple treats.

Treats can be given as a reward for blood glucose testing or when the blood glucose is at its lowest – approximately 4 to 8 hours after injection.

Good treat options include: baby carrots, snap peas, broccoli, cauliflower, green or red peppers, canned pumpkin, tofu, a kibble of your dog’s regular dog food, and/or freeze dried meat treats. Recommended commercial treats Stella & Chewy’s Carnivore Crunch, Orijen Treats and Sam’s Yams.

Some diabetic dog owners make their own treats by taking an approved canned dog food and using that is as the base to make treats. They generally will empty the can onto a cookie sheet, either cut into small pieces or smash down to about ¼ to ½ inch thickness and bake at 375 degrees Fahrenheit until dry and crispy. Some foods can be refrigerated and sliced, then baked the same way. Store baked treats in the refrigerator in a sealed container.

The calories in the treats should be considered in the overall calories requirements for the day. Treats should be given in moderation.

How Should I Exercise My Diabetic Dog?

Regular exercise is good for your dog. It can help lose or maintain weight and lower the blood sugar.

The best approach to exercising your diabetic dog is to do it regularly and routinely. Try to do the same amount of exercise every day at the same time.

Large changes in exercise routines can change insulin requirements. A new exercise, an unusually long or vigorous play session; long hike can all cause the blood sugar levels to drop too low. If you plan a change in your dog’s routine, do it slowly and gradually.

If you take a hike or do something outside your dog’s routine, take extra treats or a meal just in case your dog has a problem.

What is Insulin?

Insulin is a hormone that is formed and released by beta cells residing in the pancreas. Eating prompts the release of insulin. When insulin is not produced in sufficient quantities, it can be administered in the form of an injection.

There are various types of insulin treatments, each with a different duration of effectiveness.

A bottle of insulin is commonly referred to as a vial. All insulins are measured in units.

There are two common concentrations which will be important when you buy your insulin syringe. Some insulin’s are u-100 (100 units in a milliliter) and others are u-40 (40 units in a milliliter). Because insulin’s are different, 3 units of one insulin may not be the same as 3 units of a different insulin. It is very important to verify the type of syringe and insulin match when filling your prescription to avoid over- or under-dosing your pet.

There are several different types of insulin used on dogs. They differ by what they are made from (some are pork, some are human-based) and how long they act in the body. The short acting insulins are referred to as “regular”, medium acting are referred to as “Lente” and long acting insulins are referred to as “Ultralente”.

The most commonly used insulin’s in dogs are:

NOTE: There are several types of insulin on the market. What works on one pet may not work on a different pet.

How Often Does my Dog Need Insulin?

Your veterinarian will determine this but based on the insulin’s available in the U.S. for dogs, the most effective treatment for diabetes in dogs is administration of insulin with intermediate duration of action twice daily.
The only currently available intermediate-duration product is recombinant human neutral protamine Hagedorn (NPH) insulin.

Another type of insulin can be used in dogs called Porcine Lente insulin (Vetsulin). At the present time, it is not being sold in the United States due to problems with stability and bacterial contamination associated with the manufacturing process. Based on our sources, it is uncertain when or if the product will again be available in the United States.

Why Does My Dog Need Insulin?

Insulin is required for food to be properly processed and utilized as energy for the body. Insulin lowers the blood sugar after a meal. Deficiency of insulin, or an insensitivity of body cells to available insulin, leads to diabetes.

The goal of diabetes treatment is to supplement the insulin to regulate the blood glucose in as close to a normal range as possible.

How Should the Insulin Look?

The first time you open your insulin – look at the color and clarity of the bottle most types of insulin will look slightly cloudy but there should be no clumps or floating particles.

How Much Insulin Do I Give?

The initial dose of insulin given is 1/8 to 1/4 of a unit per pound of body weight given every 12 hours.

For example, a 20-pound dog may start on 2 units of insulin per dose. A lower dose is generally recommended with a gradual increase. It is better to start low and gradually allow the body to acclimate to the disease and avoid signs of hypoglycemia (low blood sugar).

How Do I Give the Insulin Injection?

Insulin is generally given under the skin (subcutaneous) over the back. The location of the injection should be rotated with every injection. The general method for giving insulin is as follows:

Gather your equipment to give the insulin injection. The bottle of insulin, syringe, cotton ball, alcohol…and your glasses if you wear them (It can be difficult to see the small print on the numbers).

What If I get Air in My Syringe?

Air in the syringe means that you will not get the correct dose of insulin.

If you are drawing up your insulin, you have the syringe in the vial of insulin and you see you are getting air, inject the insulin (and air) that is in the syringe back in the bottle. Try again. You can sometimes gently tap the syringe (flick the syringe case with your index finger) to encourage the air bubble to go to the top to dispose.

If you have taken the insulin out of the bottle and notice that there is air in the syringe, the best approach is to disposed of that insulin and pull up the correct dose.

When Should I Give the Insulin?

Most dogs are on twice daily insulin. This should be given 12 hours apart. As you start therapy on your diabetic dog, pick a time that works for you that is 12 hours a part. For some pet owners, this may be 6 am and 6 pm. For others it may be 4 am and 4 pm. Whatever works for you is fine. Try to give the insulin within an hour of the scheduled dose time.

If you give insulin once daily – give it at the same time every day.

How Do I Store My Insulin?

Every insulin is slightly different. Most all are sensitive to light. Some manufacturers recommend that the insulin be stored in the refrigerator and others are ok at room temperature. It should always be stored out of direct light. I generally recommend that when you open a new box with insulin – mark the date on the box with permanent marker and keep your insulin stored in the box.

All insulin’s are sensitive to extremes in temperature such as heat and freezing. Review the manufacturer’s recommendations for storage and for expiration dates.

Most commonly used insulins have the following recommendations:

How Long Does the Insulin Last?

Please follow the recommendation from your veterinarian. Some insulin manufacturers recommend a new vial be started every 30 days and others recommend every 3 months. Realistically, very little insulin is used in 30 days for most dogs. This is the ideal recommendation.

Most veterinarians recommend that the dog owner examine the insulin daily to ensure there are no clumps, particles that won’t dissolve or an abnormal color. Dispose of the bottle when it expires (check date on the bottle) or 6 months after it is opened. Most insulin’s have been found to stay effective for this time.

It is possible that as the insulin ages, it becomes less effective.

When opening a new bottle, write the date on the bottle or box and in your calendar.

Why Do I Need to Roll the Insulin Bottle?

It is recommend to gently “roll” the insulin bottle to disperse the powdered insulin in the liquid. Shaking can damage the insulin molecules.

To roll the bottle, place it between the palms of your hands and gently a roll it between your palms 2 to 3 times. This is enough to disperse the insulin.

If you draw a dose of insulin that isn’t properly mixed, you may either get too much or not enough of the proper concentration. Some insulin’s settle out very quickly so it is recommend to gently roll the bottle between your palms a few times to disperse the contents then immediately draw the insulin in the syringe.

Why Can’t I Shake My Dogs Insulin?

Gently rolling of the insulin between your palms is all that is needed to gently mix the insulin. The insulin is a very fine powder that is suspended in the liquid.

Rolling the insulin is better for a few reasons:

First, shaking denatures the protein, hurts the insulin molecule so it doesn’t work correctly.

Second, shaking creates air bubbles, which can also act to denature the protein, inactivating the insulin. The air also makes it more likely to pull up air bubbles in the syringe that are hard to remove. If you include the air in your dose, then you are not giving the proper dose to your dog.

How Much Insulin Should You Keep On Hand?

It is recommended that you keep a spare vial of insulin on hand. This way if you happen to be out or drop and break a vial, you have a spare.

Diabetic pet owners will tell you it is no fun trying to find insulin on the weekend if something happens.

Can I Freeze My Dogs Insulin to Preserve it?

Insulin is delicate. Freezing will render the insulin inactive.

My Insulin has Clump or Particles That Aren’t Dissolving

If you notice clumps in your insulin, particles that won’t dissolve, an abnormal color or anything else that seems suspicious, stop using that vial and dispose.

Open a new insulin bottle for use.

What Type of Insulin Syringe Should I Use?

There are three things you need to know when buying insulin syringes.

When you go to the pharmacy to buy syringes make sure you buy the one that works with your insulin. Know if you need U-100 or U-40.

A commonly used syringe is a 31 gauge (which is a very small needle). For example, this is a common syringe size that pet owners like:

What If I have U-40 Insulin and U-100 Syringes?

There is a formula to convert U-40 and U-100 syringes. Go to this Link

How do You Convert Insulin Units to Milliliters?

Ideally, if you have the insulin and syringes that match – you don’t need to do this. Mistakes happen when pet owners start trying to do various conversions.

U-100 means there are 100 units in 1 milliliter (mL or ml).
30 units of a U-100 insulin are equal to 0.3 milliliters (0.3 ml).

I have a chart that will help you. Go to: How to Convert U-100 Insulin in Units to Milliliters.

Where Can I Buy Insulin Syringes?

You can buy your insulin syringes from your vet or at most pharmacies. You don’t need a prescription to buy them. You can also buy them online at several pharmacies. Choose a pharmacy with which you are familiar and comfortable. It is important to be frugal but there have been reports and recalls of insulin syringes that are mismarked from low cost syringe producers.

Insulin syringes are cheapest by the carton, which contains 100 syringes.

How Many Times Can I Use the Insulin Syringe?

Insulin syringes are made to be disposable, to be used once and tossed. However we as veterinarians and pet owner care givers are frugal. Boxes of 100 needles run about $20 to $45 dollars depending on where you shop.

If you are using 2 syringes a day – that is 60 syringes a month.

Ideally, use the syringe once. This minimizes the chances of infections that can be caused by a dirty needle. If you must reuse the syringe, use them only twice. The needles dull quickly because they are made to be used once. When they are dull, it is more uncomfortable for your dog that may make him resent the injection.

I Accidentally Bent the Needle On The Insulin Syringe – Can I bend It Back?

The insulin syringe needles are very fine and fragile. They will bend easily but don’t bend them back. Because they are so thin, bending them back can create a weak spot that can break. What can happen is that you bend it back, give the injection and that additional stress on the needle makes the needle break off in the dog’s skin.

If the needle bends regularly, try a needle that is a little stronger. This means you would pick a gauge size that is a lower number. If you are using a 31-gauge needle, try a 29 gauge and see if that bends less and is easier for you to use. This slight difference doesn’t make a difference in comfort to most dogs.

Some pharmacies offer free syringe samples. This is a great way to see what works best for you and your dog.

My Syringe Needle Accidentally Touched Something – What Do I Do?

If you have drawn up your insulin in the syringe and it makes contact with your finger, table or anything else, the best and safest thing to do is to throw it away and start over.

I Drew Up Insulin and Now Can’t Find My Dog. Now What?

If you rolled the bottle and the contents were mixed properly before mixing up the insulin, it should be ok in the syringe for a few hours. If your insulin is normally stored in the refrigerator, store the syringe in the refrigerator with the needle side tilted up. This prevents the needle form clogging.

Before injecting, gently tilt the syringe up and down then give. ?If it is more than 2 hours, dispose of the insulin. Also – read the section on “What If I’m Late Giving the Insulin?”

Should I Recap the Insulin Syringe?

Recapping syringes is a big “no-no” in human medicine due to the risk of human HIV and hepatitis. These diseases are not a problem in dogs but in general, re-capping syringes is not recommend to prevent you from sticking yourself. With that being said, veterinary professionals recap needles daily and routinely stick themselves without it being a big deal.

If you re-cap a syringe, keep one hand stable and move one hand to recap. If you are moving both hands at the same time there is a higher risk of sticking yourself.

They make needle clippers that remove the needle but these need to be used with care. As the small needle bits can be dangerous.

The safest approach may be to not re-cap your syringe and dispose of immediately in a sharps container.

What Do I do with My Used Syringes and Lancets?

You can dispose of your needles, syringes and lancets a few different ways. You can buy “sharps” containers similar to what they use in human and veterinary hospitals. The sharps containers are thick plastic that cannot be punctured. You simply place the syringe and needle in the box until it is full. When it is full, you close the top to secure. “Sharps” containers can be purchased at some pharmacies and online.

Some pet owners use a plastic milk jug, empty laundry detergent bottle or large soft drink bottle as their sharps container. When full, place the lid and tape. This can then be placed in your regular trash. Most homes produce very little sharps and this container can then be disposed of in your regular trash (after it is sealed). Check the rules for your area. A website that can help in determining the regulations in your area: http://www.safeneedledisposal.org

How Many Times Can I Use the Lancet on My Dog?

Lancets are made to be used one and thrown away. Ideally, use them once and toss. If you must reuse the lancet, it is recommended use them only twice. The needle edge dulls quickly because they are only made to be used once. When they are dull, it is more uncomfortable for your dog that may make him resent the testing.

How Much Insulin Should I Give if My Dog Won’t Eat

I’d recommend that you ask your vet this question but the answer is generally as follows:

What If I’m Late Giving the Insulin?

On occasion, you may forget to give your dog’s insulin or are unable to get home.

If you are unable or forget to give your dog’s insulin at the regular time, these are the general recommendations:

  1. If you are late by 1 to 2 hours – it is ok to give the insulin using your regular routine. The next day- move the next shot by a little then get back on your routine.
  2. If you are late by more than 2 hours – it is preferred to skip the injection.