Overview of Canine Lymphedema

Lymphedema is an abnormal accumulation of protein-rich lymph fluid into tissue spaces caused by obstruction of flow in lymphatic vessels or through lymph nodes. It may be primary or secondary. Primary/congenital lymphedema is usually present at birth or by several months of age.

Lymphedema is more common in dogs than cats and no sex predilection has been reported. It is often congenital in English bulldogs. Although lymphedema can affect all breeds, dogs with a familial predisposition include poodles, Labrador retrievers and Old English sheepdogs.

Causes of Primary Lymphedema in Dogs

Idiopathic (unknown cause)

Hereditary/congenital malformation of the lymphatic system, which is the network of vessels that carries protein-rich lymph fluid through the body.

Causes of Secondary Lymphedema

Secondary damage to lymphatic vessels or lymph nodes

Trauma

Infection/inflammation

Neoplasia (cancer)

Radiation therapy

What to Watch For

Symptoms of Lymphedema in Dogs may include: 

Swelling of the legs that typically starts at the foot and advances toward the body, which can occur in one or multiple limbs, most commonly in the hind legs

Swelling that may affect the underside of the chest, abdomen, ears and tail

Uncommonly, lameness and pain

Diagnosis of Lymphedema in Dogs

Complete blood cell count (CBC)

Biochemical profile

Urinalysis

Heartworm test

Fine-needle aspirate of the affected tissue

Lymphangiography, which is the injection of dye directly into the lymphatic system

Chest and abdominal X-rays, although often within normal limits, may be of benefit in ruling out other disorders

Treatment of Lymphedema in Dogs

There is no curative therapy, treatment is aimed at minimizing the symptoms.

Pressure wraps

Warm water massage

Antibiotics for secondary infections

Benzopyrones, a group of drugs that may help reduce swelling

Home Care and Prevention

Puppies with severe lymphedema may die with or without treatment. Administer all medication and follow all recommendations as directed by your veterinarian. If your dog’s condition is not improving or getting worse, seek veterinary attention at once.

There is no preventative care for primary lymphedema.