Cefotaxime (Claforan®) for Dogs and Cats

Overview of Cefotaxime for Canines and Felines

Brand Names and Other Names of Cefotaxime

Uses of Cefotaxime for Dogs and Cats

Cefotaxime is used in both dogs and cats to treat a variety of bacterial infections, including:

Precautions and Side Effects

1) Injection site inflammation following intravenous administration and pain, induration, and tenderness after intramuscular injection.

2) Hypersensitivity reactions – rash, pruritus, fever, eosinophilia, urticaria, and anaphylaxis.

3) Gastrointestinal problems such as colitis, diarrhea, and vomiting. Symptoms of pseudomembranous colitis may appear during or after treatment.

Drug Interactions

1. Aminoglcosides – aminoglycoside toxicity may be enhanced (monitor renal function carefully)

2. Anticoagulants – hypoprothrombinemic effects of anticoagulants may be increased

3. Polypeptide antibiotics – their nephrotoxic effects may be enhanced. Monitor renal function.

4. Probenecid – inhibits renal tubular secretion of cefotaxime

How Cefotaxime is Supplied

Dosing Information of Cefotaxime for Dogs and Cats