Etodolac (EtoGesic®, Lodine®) for Dogs

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Overview of Etodolac (EtoGesic®) for Dogs

  •  Etodolac, commonly known by the names EtoGesic® and Lodine®, is primarily used to treat pain and inflammation associated with arthritis in dogs. Some dosage forms have limited availability. 
  • There are a number of drugs related to aspirin and capable of reducing pain, fever and inflammation. As a group, these drugs are called nonsteroidal anti-inflammatory drugs or NSAIDs.
  • Etodolac works by inhibiting formation of body chemicals called prostaglandins.
  • Etodolac is a prescription drug and can only be obtained from a veterinarian or by prescription from a veterinarian.
  • Brand Names and Other Names of Etodolac for Dogs

  • This drug is registered for use in humans and animals.
  • Human formulations: Lodine® (Wyeth-Ayerst)
  • Veterinary formulations: EtoGesic® (Fort Dodge)
  • Uses of Etodolac for Dogs

  • Etodolac is primarily used to treat pain and inflammation associated with arthritis.
  • Precautions and Side Effects

  • While generally safe and effective when prescribed by a veterinarian, etodolac can cause side effects in some dogs.
  • Etodolac should not be used in dogs with known hypersensitivity or allergy to the drug.
  • Etodolac should be avoided in dogs with liver, heart or blood abnormalities.
  • Etodolac should also be avoided in dogs with gastrointestinal disorders, including ulcers. Never combine this drug with aspirin, other NSAIDs, or cortisone-like drugs (prednisone) unless specifically directed by a veterinarian.
  • Etodolac may interact with other medications. Consult with your veterinarian to determine if other drugs your pet is receiving could interact with etodolac. Such drugs include aspirin, ibuprofen, corticosteroids, phenobarbital, probenecid, methotrexate, furosemide and other diuretics, and certain antibiotics.
  • The most common adverse effects associated with etodolac are vomiting, diarrhea, lethargy and lack of appetite.
  • Stomach ulcers and kidney impairment are possible with this drug, but are less commonly observed when compared to other NSAIDs.
  • Not recommended for dogs less than 12 months of age, or in breeding, pregnant or lactating pets. 
  • Due to difficulty dosing, dogs under 10 pounds should not receive etodolac.
  • At this time, etodolac should not be administered to cats until further studies are completed.
  • How Etodolac Is Supplied

  • Etodolac is available in 150 mg, 300 mg, 400 mg, and 500 mg tablets. Extended release tablets available in sizes 400 mg, 500 mg and 600 mg. Capsules available in 200 mg, 300 mg and 400 mg sizes. 
  • Etodolac is also available as an injectable drug in the concentration of 100 mg/ml. 
  • Available of some formulations has been limited. 
  • Dosing Information of Etodolac for Dogs

  • Medication should never be administered without first consulting your veterinarian.
  • Etodolac is dosed at 5 to 6 mg per pound (10 to 15 mg/kg) once daily. 
  • Not recommended for use in cats. 
  • Can be given with or without food. 
  • The duration of administration depends on the condition being treated, response to the medication and the development of any adverse effects. Be certain to complete the prescription unless specifically directed by your veterinarian. Even if your pet feels better, the entire treatment plan should be completed to prevent relapse or prevent the development of resistance.
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