Carprofen (Rimadyl, Novox, Quellin) Toxicity in Dogs

Overview of Carprofen Toxicity in Dogs

Carprofen toxicity describes the symptoms of poisoning associated with the administration of Carprofen (commonly known also by the names of Rimadyl®, Novox and Quellin), a non-steroidal anti-inflammatory medication used for the treatment of arthritis. These drugs suppress inflammation and pain by inhibiting synthesis of the class of compounds called prostaglandins. Rimadyl® toxicity can cause damage to the gastrointestinal tract, liver and kidneys.

Below we will use the name carprofen and Rimadyl interchangeable. Rimadyl is the most common name brand of carprofen on the market.

Carprofen toxicity in dogs generally occurs as the result of one of the following:

What to Watch For

Signs of carprofen toxicity in dogs may include:

Diagnosis of Carprofen Toxicity in Dogs

A history of Rimadyl® administration or accidental ingestion of an inappropriately high dose of Rimadyl® is helpful to your veterinarian in determining the cause of your dog’s illness. In addition to obtaining a complete history and performing a thorough physical examination, your veterinarian will likely perform the following tests:

Treatment of Carprofen Toxicity in Dogs

Hospitalization is necessary to provide definitive treatment and may require two to five days. Other treatments for dogs may include:

Home Care and Prevention

If accidental ingestion has occurred, remove any remaining pills from the pet’s environment. Take your dog to a veterinarian as soon as possible for treatment of an overdosage of Rimadyl®.

If you have been administering Rimadyl® and you note vomiting, melena, pale or yellow gums or loss of appetite, stop administration of Rimadyl® and take your dog to a veterinarian as soon as possible.

To prevent toxicity, never exceed the dose of Rimadyl® prescribed by your veterinarian. Administer Rimadyl® with food to help prevent stomach upset.